Squamous Cell Carcinoma
Squamous Cell Carcinoma is a form of skin cancer that can occur in a variety of different organs, these include the skin, lips, esophagus, urinary bladder, prostate, lungs, vagina, and cervix. Squamous cell carcinoma can be classified into different types, we will list the different types here. These types usually are named depending where you will find the skin cancer located on the body.
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Adenoid Squamous Cell Carcinoma is characterized by tubular microscopic patterns and keratinocyte acantholysis.
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Celar Cell Squamous Cell Carcinoma is characterized by keratinocytes that appear clear because of Hydropic swelling.
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Spindle Cell Squamous Cell Carcinoma is characterized by spindle-shaped atypical cells.
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Signet-ring Cell Squamous Cell Carcinoma are characterized by concentric rings made of keratin and large vacuoles corresponding to markedly dilated endoplasmic reticulum.
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Basaloid Squamous Cell Carcinoma is a form of skin cancer that is usually found on the tongue.
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Verrucous Carcinoma is a form of skin cancer that occurs from dipping tobacco, or snuff. It is often called dipper's cancer.
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Keratoacanthoma originates in the pilosebaceous glands.
Treatment for Squamous Cell Carcinoma can vary depending on what type you have. Although there are not many different treatments that are widely used. There are a couple treatments that are still being tested but are showing promise, and in time may be the best treatment for whatever form of Squamous Cell Carinoma you have.
Mohs Surgery is the most frequently used form of treatment for SCC, that is because the other types of treatment have not gotten approval from the FDA as of yet. Not only has it been used to treat skin cancer, but also has been used to treat SCC of the mouth, throat, and neck.
Imiquimod has been used with success on SCC in situ of the skin and the penis, but the morbidity and discomfort of the treatment is severe. The only benefit of using this procedure is that after the area is treated there is no scarring. Imiquimod is not approved by the FDA as of yet.
There is another treatment that an Australian Biopharmaceutical compant Clinuvel Pharmaceuticals Limited had started clinical trials with. This treatment uses a melanocyte0stimulating hormone called Afamelanotide. It provides photoprotection for organ transplant patients against SCC of the skin and actinic keratosis.
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